United States securities and exchange commission logo May 18, 2021 Daniel Hirsch Chief Financial Officer Todos Medical Ltd. 121 Derech Menachem Begin, 30th Floor Tel Aviv, 6701203 Israel Re: Todos Medical Ltd. Registration Statement on Form S-1 Filed May 13, 2021 File No. 333-256053 Dear Mr. Hirsch: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Kasey Robinson at 202-551-5880 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Carl Sherer